Simvastatin is butanoic acid, 2,2-dimethyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-1-naphthalenyl ester, ]. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, which is an early and rate-limiting step in the biosynthesis of cholesterol. This is an inhibitor of 3-hydroxy-3-methylglutaryl- coenzyme A (HMG-CoA) reductase. After oral ingestion, simvastatin, which is an inactive lactone, is hydrolyzed to the corresponding β-hydroxyacid form. ZOCOR (simvastatin) is a lipid-lowering agent that is derived synthetically from a fermentation product of Aspergillus terreus. You may report side effects to FDA at 1-80. For more information, ask your doctor or pharmacist.Ĭall your doctor for medical advice about side effects. These are not all the possible side effects of Zocor. Tell the doctor if you have any side effect that bothers you or that does not go away. cold symptoms ( stuffy nose, sneezing or sore throat).The most common side effects of Zocor include: Get medical help right away, if you have any of the symptoms listed above. Zocor may cause serious side effects including: It is not known if Zocor is safe and effective in children younger than 10 years of age. Zocor belongs to a class of drugs called Lipid-Lowering Agents, Statins, HMG-CoA Reductase Inhibitors. Zocor may be used alone or with other medications. Zocor (simvastatin) is a prescription medicine used to lower levels of "bad" cholesterol (low-density lipoprotein or LDL) and to increase levels of “good” cholesterol (high-density lipoprotein or HDL) and to lower triglycerin as well as to reduce the risk of stroke and heart attacks. With future research, experts hope to provide more clear recommendations for the use of supplements as a form of cholesterol-lowering treatment.Find Lowest Prices on What is Zocor and how is it used? Rather, supplements and dietary changes may be a useful addition to treatment plans for high cholesterol. Patients also shouldn’t replace any other cholesterol-lowering drugs with natural remedies. However, authors stress the fact that natural remedies cannot replace statin therapy, which is a tried-and-true way to lower cholesterol and risk for heart events. Since their treatment options are limited, supplements may help further reduce cholesterol levels. Many patients who can’t take statins will take non-statin drugs like ezetimibe and PCSK9 inhibitors. Muscle pain is one of the most common side effects associated with statins. There are also few downsides, as it’s unlikely that supplements or dietary changes would have interactions with current medications.Īuthors also explain that natural remedies may be recommended for patients who can’t tolerate statins. Experts believe the addition of supplements could complement existing treatments. Based on this evidence, authors believe it’s reasonable to consider such alternatives in certain situations.įor example, natural remedies may be useful for high-risk patients taking statins who still don’t have their cholesterol under control. However, studies show that these remedies are generally safe, with virtually no adverse effects, and have some cholesterol-lowering benefits. There’s not enough evidence to say how well they work and for which patients they’ll work best. Studies have tested a number of different supplements, such as red yeast rice, omega-3 fatty acids, spirulina, soy proteins, green tea, lupin, garlic fibers, bergamot and berberine. While additional research is needed on the topic, authors hope the paper provides some groundwork for incorporating natural remedies into modern medicine.īased on the latest evidence, authors explain that certain foods and supplements may aid in cholesterol reduction. The statement’s key purpose was to provide treatment options for patients who can’t take statins due to side effects. Nutraceuticals are foods or supplements that have special health benefits. Written by a team of experts, this statement summarized everything we know about natural remedies for lowering cholesterol, sometimes referred to as nutraceuticals. For patients who can’t tolerate cholesterol-lowering statins, natural remedies like bergamot, garlic and green tea may be a useful alternative, based on a recent statement published in the Journal of the American College of Cardiology.
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